Pgf - placental growth factor

Enables identical protein binding activity. Involved in several processes, including animal organ regeneration; positive regulation of angiogenesis; and positive regulation of endothelial cell proliferation. Located in extracellular space. Used to study congestive heart failure and myocardial infarction. Biomarker of diabetic retinopathy; end stage renal disease; pre-eclampsia; and status epilepticus. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor). [provided by Alliance of Genome Resources, Apr 2022]