P2rx5 - purinergic receptor P2X, ligand-gated ion channel, 5
Alias:
P2X5
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Sequence Homology
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Enables extracellularly ATP-gated cation channel activity. Predicted to be involved in several processes, including positive regulation of calcium ion import across plasma membrane; regulation of skeletal muscle tissue regeneration; and response to ATP. Predicted to act upstream of or within cell surface receptor signaling pathway. Predicted to be located in cytosol and plasma membrane. Predicted to be integral component of nuclear inner membrane. Is expressed in several structures, including forelimb bud; nervous system; neural ectoderm; olfactory epithelium; and retina. Orthologous to human P2RX5 (purinergic receptor P2X 5). [provided by Alliance of Genome Resources, Apr 2022]