Rnf111 - ring finger 111

Enables ubiquitin protein ligase activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within several processes, including cellular protein metabolic process; positive regulation of protein ubiquitination; and positive regulation of transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. Part of protein-containing complex. Is expressed in several structures, including heart; nervous system; testis; and urinary system. Orthologous to human RNF111 (ring finger protein 111). [provided by Alliance of Genome Resources, Apr 2022]