Smarca5 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ATP-dependent activity, acting on DNA. Predicted to contribute to histone binding activity. Involved in rDNA heterochromatin assembly. Acts upstream of or within cellular response to leukemia inhibitory factor; chromatin organization; and positive regulation of transcription, DNA-templated. Located in nucleus. Part of ISWI-type complex and chromatin silencing complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SMARCA5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5). [provided by Alliance of Genome Resources, Apr 2022]