KNSTRN - Kinetochore Localized Astrin (SPAG5) Binding Protein
Alias:
SKAP
HSD11
ROCHIS
C15orf23
TRAF4AF1
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Basic Information
Sequence Homology
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Enables microtubule plus-end binding activity and protein homodimerization activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; mitotic sister chromatid segregation; and regulation of attachment of spindle microtubules to kinetochore. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and ruffle. Implicated in actinic keratosis and skin squamous cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]