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ENRat
Nox4 - NADPH oxidase 4
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Enables NAD(P)H oxidase H2O2-forming activity. Involved in several processes, including cellular response to cAMP; cellular response to gamma radiation; and positive regulation of stress fiber assembly. Located in several cellular components, including apical plasma membrane; focal adhesion; and perinuclear endoplasmic reticulum. Part of NADPH oxidase complex. Colocalizes with stress fiber. Used to study hypertension. Biomarker of hypertension and non-alcoholic steatohepatitis. Orthologous to human NOX4 (NADPH oxidase 4). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
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Nox4 Genetics information (+)
mRatBN7.2
Sequence Homology
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* This data comes from NCBI.
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