Prss12 - serine protease 12

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in exocytosis and zymogen activation. Predicted to act upstream of or within proteolysis. Predicted to be located in axon; cytoplasmic vesicle; and synapse. Predicted to be active in several cellular components, including dendrite; synaptic cleft; and terminal bouton. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and intellectual disability. Orthologous to human PRSS12 (serine protease 12). [provided by Alliance of Genome Resources, Apr 2022]