Enables protein domain specific binding activity. Involved in negative regulation of transcription by RNA polymerase II; protein export from nucleus; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including annulate lamellae; kinetochore; and nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human XPO1 (exportin 1). [provided by Alliance of Genome Resources, Apr 2022]