Enables G-protein alpha-subunit binding activity; calcium ion binding activity; and guanyl-nucleotide exchange factor activity. Involved in regulation of protein targeting; response to cisplatin; and small GTPase mediated signal transduction. Located in several cellular components, including Golgi apparatus; cytoplasmic vesicle; and rough endoplasmic reticulum. Is extrinsic component of Golgi membrane. Orthologous to human NUCB1 (nucleobindin 1). [provided by Alliance of Genome Resources, Apr 2022]