Predicted to enable cysteine desulfurase activity and protein homodimerization activity. Predicted to be involved in iron incorporation into metallo-sulfur cluster. Predicted to be located in mitochondrial matrix and nucleoplasm. Predicted to be active in cytosol; mitochondrion; and nucleus. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human NFS1 (NFS1 cysteine desulfurase). [provided by Alliance of Genome Resources, Apr 2022]