Dgat1 - diacylglycerol O-acyltransferase 1

Enables diacylglycerol O-acyltransferase activity; diacylglycerol binding activity; and fatty acid binding activity. Involved in several processes, including insulin secretion; positive regulation of hepatic stellate cell activation; and regulation of lipid metabolic process. Located in intracellular membrane-bounded organelle and plasma membrane. Biomarker of chronic kidney disease and nephrotic syndrome. Human ortholog(s) of this gene implicated in cardiomyopathy and congenital diarrhea 7 with exudative enteropathy. Orthologous to human DGAT1 (diacylglycerol O-acyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]