Fgfr3 - fibroblast growth factor receptor 3

Enables fibroblast growth factor binding activity and fibroblast growth factor-activated receptor activity. Involved in cell-cell signaling; fibroblast growth factor receptor signaling pathway; and positive regulation of cell population proliferation. Located in cell surface; cytoplasm; and nucleus. Biomarker of chondrosarcoma. Human ortholog(s) of this gene implicated in several diseases, including Crouzon syndrome-acanthosis nigricans syndrome; LADD syndrome; SADDAN; bone development disease (multiple); and carcinoma (multiple). Orthologous to human FGFR3 (fibroblast growth factor receptor 3). [provided by Alliance of Genome Resources, Apr 2022]