Asah1 - N-acylsphingosine amidohydrolase 1

Predicted to enable N-acylsphingosine amidohydrolase activity; nuclear receptor binding activity; and transcription corepressor activity. Involved in lung development and response to organic substance. Predicted to be located in extracellular space; lysosome; and nucleus. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Orthologous to human ASAH1 (N-acylsphingosine amidohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]