Ihh - Indian hedgehog signaling molecule

Predicted to enable calcium ion binding activity and patched binding activity. Involved in several processes, including liver regeneration; maternal process involved in female pregnancy; and response to estradiol. Predicted to be located in extracellular matrix and plasma membrane. Predicted to be active in extracellular space. Biomarker of osteoarthritis. Human ortholog(s) of this gene implicated in acrocapitofemoral dysplasia; brachydactyly type A1; retinopathy of prematurity; and syndactyly type 1. Orthologous to human IHH (Indian hedgehog signaling molecule). [provided by Alliance of Genome Resources, Apr 2022]