Tcf4 - transcription factor 4

Enables bHLH transcription factor binding activity and double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nucleus. Predicted to be part of beta-catenin-TCF7L2 complex. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy and Pitt-Hopkins syndrome. Orthologous to human TCF4 (transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]