Ghsr - growth hormone secretagogue receptor

Enables growth hormone secretagogue receptor activity and peptide hormone binding activity. Involved in several processes, including regulation of digestive system process; regulation of secretion by cell; and response to peptide hormone. Acts upstream of or within negative regulation of insulin secretion. Located in plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is integral component of synaptic membrane. Used to study middle cerebral artery infarction. Biomarker of isolated growth hormone deficiency; multiple endocrine neoplasia; obstructive sleep apnea; status epilepticus; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GHSR (growth hormone secretagogue receptor). [provided by Alliance of Genome Resources, Apr 2022]