Enables enzyme binding activity. Involved in several processes, including NMDA selective glutamate receptor signaling pathway; modification of postsynaptic actin cytoskeleton; and neurotransmitter receptor localization to postsynaptic specialization membrane. Located in neuron projection; neuronal cell body; and perinuclear region of cytoplasm. Is active in glutamatergic synapse; postsynaptic density; and presynapse. Orthologous to human KALRN (kalirin RhoGEF kinase). [provided by Alliance of Genome Resources, Apr 2022]