Rps6kb1 - ribosomal protein S6 kinase B1

Enables several functions, including ATP binding activity; PDZ domain binding activity; and protein phosphatase 2A binding activity. Involved in several processes, including long-term memory; positive regulation of skeletal muscle tissue growth; and response to peptide hormone. Located in several cellular components, including cell surface; cytosol; and perinuclear region of cytoplasm. Is active in synapse. Biomarker of several diseases, including autosomal dominant polycystic kidney disease; hyperinsulinism; muscular atrophy; obesity; and primary biliary cholangitis. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1). [provided by Alliance of Genome Resources, Apr 2022]