Ltbp3 - latent transforming growth factor beta binding protein 3

Predicted to enable transforming growth factor beta binding activity. Predicted to be involved in several processes, including elastic fiber assembly; positive regulation of mesenchymal stem cell differentiation; and positive regulation of mesenchymal stem cell proliferation. Predicted to act upstream of or within several processes, including negative regulation of bone mineralization; negative regulation of chondrocyte differentiation; and positive regulation of bone resorption. Predicted to be located in collagen-containing extracellular matrix and extracellular region. Human ortholog(s) of this gene implicated in brachyolmia-amelogenesis imperfecta syndrome and geleophysic dysplasia 3. Orthologous to human LTBP3 (latent transforming growth factor beta binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]