Trpv1 - transient receptor potential cation channel, subfamily V, member 1

Enables several functions, including ATP binding activity; calmodulin binding activity; and ligand-gated ion channel activity. Involved in several processes, including calcium ion import across plasma membrane; cellular response to organonitrogen compound; and cellular response to temperature stimulus. Acts upstream of or within response to heat and response to pH. Located in several cellular components, including external side of plasma membrane; neuronal cell body; and postsynaptic membrane. Is integral component of plasma membrane. Used to study myocardial infarction and reflex epilepsy. Human ortholog(s) of this gene implicated in migraine. Orthologous to human TRPV1 (transient receptor potential cation channel subfamily V member 1). [provided by Alliance of Genome Resources, Apr 2022]