Dvl1 - dishevelled segment polarity protein 1

Enables protein kinase binding activity and small GTPase binding activity. Involved in several processes, including dendritic spine morphogenesis; positive regulation of excitatory postsynaptic potential; and positive regulation of neuron projection arborization. Located in several cellular components, including dendritic spine; growth cone; and postsynaptic density. Colocalizes with microtubule. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in DiGeorge syndrome and autosomal dominant Robinow syndrome 2. Orthologous to human DVL1 (dishevelled segment polarity protein 1). [provided by Alliance of Genome Resources, Apr 2022]