Gabbr2 - gamma-aminobutyric acid type B receptor subunit 2

Enables G protein-coupled GABA receptor activity. Involved in gamma-aminobutyric acid signaling pathway and neuron-glial cell signaling. Is active in GABA-ergic synapse and glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 59 and nicotine dependence. Orthologous to human GABBR2 (gamma-aminobutyric acid type B receptor subunit 2). [provided by Alliance of Genome Resources, Apr 2022]