Usf1 - upstream transcription factor 1

Enables DNA binding activity; DNA-binding transcription factor activity; and identical protein binding activity. Contributes to DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in glucose metabolic process and positive regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in cardiovascular system disease and type 2 diabetes mellitus. Orthologous to human USF1 (upstream transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]