Pafah1b1 - platelet-activating factor acetylhydrolase 1b, regulatory subunit 1

Enables dynein intermediate chain binding activity. Involved in several processes, including establishment of centrosome localization; generation of neurons; and negative regulation of neuron projection development. Located in several cellular components, including central region of growth cone; neuronal cell body; and nuclear envelope. Part of 1-alkyl-2-acetylglycerophosphocholine esterase complex and kinesin complex. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in lissencephaly and lissencephaly 1. Orthologous to human PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1). [provided by Alliance of Genome Resources, Apr 2022]