Kcnj11 - potassium inwardly-rectifying channel, subfamily J, member 11

Enables several functions, including ankyrin binding activity; inorganic cation transmembrane transporter activity; and protein C-terminus binding activity. Involved in several processes, including cation transport; cellular response to nicotine; and response to ischemia. Located in several cellular components, including axolemma; cell body fiber; and cytoplasmic vesicle. Part of inward rectifying potassium channel. Biomarker of brain disease (multiple); glucose metabolism disease (multiple); hypertension; and sciatic neuropathy. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 2 and glucose metabolism disease (multiple). Orthologous to human KCNJ11 (potassium inwardly rectifying channel subfamily J member 11). [provided by Alliance of Genome Resources, Apr 2022]