Akap12 - A kinase (PRKA) anchor protein (gravin) 12
Alias:
Srcs5
SSeCKS
Tsga12
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable adenylate cyclase binding activity. Involved in modulation of chemical synaptic transmission. Is active in Schaffer collateral - CA1 synapse. Is expressed in central nervous system; gut; neural ectoderm; renal interstitium; and retina. Human ortholog(s) of this gene implicated in chronic kidney disease; colorectal carcinoma; and juvenile myelomonocytic leukemia. Orthologous to human AKAP12 (A-kinase anchoring protein 12). [provided by Alliance of Genome Resources, Apr 2022]