Cyp8b1 - cytochrome P450 family 8 subfamily B member 1
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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Related Mouse Models
References Literature
Enables sterol 12-alpha-hydroxylase activity. Involved in bile acid signaling pathway; response to cholesterol; and response to nutrient levels. Predicted to be located in endoplasmic reticulum membrane. Biomarker of extrahepatic cholestasis; non-alcoholic fatty liver disease; and premature menopause. Orthologous to human CYP8B1 (cytochrome P450 family 8 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]