Actb - actin, beta

Enables protein kinase binding activity. Involved in several processes, including cellular response to electrical stimulus; regulation of cyclin-dependent protein serine/threonine kinase activity; and regulation of norepinephrine uptake. Located in several cellular components, including actin cytoskeleton; membrane raft; and postsynaptic density. Part of protein-containing complex. Used to study non-alcoholic fatty liver disease. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome. Orthologous to human ACTB (actin beta). [provided by Alliance of Genome Resources, Apr 2022]