Tgfb2 - transforming growth factor, beta 2

Enables identical protein binding activity and protein N-terminus binding activity. Involved in several processes, including animal organ development; negative regulation of release of sequestered calcium ion into cytosol; and regulation of apoptotic process. Located in several cellular components, including basement membrane; secretory granule; and trans-Golgi network. Biomarker of diabetic neuropathy; myocardial infarction; and osteochondrodysplasia. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 4 and colorectal cancer. Orthologous to human TGFB2 (transforming growth factor beta 2). [provided by Alliance of Genome Resources, Apr 2022]