Stxbp2 - syntaxin binding protein 2

Enables syntaxin-1 binding activity and syntaxin-3 binding activity. Involved in positive regulation of mast cell degranulation and response to acidic pH. Located in apical plasma membrane; cytoplasm; and lamellipodium. Part of protein-containing complex. Colocalizes with secretory granule. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 5. Orthologous to human STXBP2 (syntaxin binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]