Grk1 - G protein-coupled receptor kinase 1

Enables rhodopsin kinase activity. Involved in protein autophosphorylation; response to light stimulus; and response to xenobiotic stimulus. Predicted to be located in photoreceptor outer segment. Predicted to be active in cytoplasm. Used to study congestive heart failure. Biomarker of retinal disease. Human ortholog(s) of this gene implicated in Oguchi disease-2 and night blindness. Orthologous to human GRK1 (G protein-coupled receptor kinase 1). [provided by Alliance of Genome Resources, Apr 2022]