Gtf2b - general transcription factor IIB

Predicted to enable several functions, including RNA polymerase II core promoter sequence-specific DNA binding activity; RNA polymerase II general transcription initiation factor activity; and TBP-class protein binding activity. Predicted to be involved in several processes, including RNA polymerase II core complex assembly; positive regulation of core promoter binding activity; and transcription initiation from RNA polymerase II promoter. Predicted to be located in chromosome and nuclear body. Predicted to be part of transcription factor TFIID complex and transcription preinitiation complex. Predicted to be active in nucleus. Orthologous to human GTF2B (general transcription factor IIB). [provided by Alliance of Genome Resources, Apr 2022]