Gnaq - G protein subunit alpha q

Enables alkylglycerophosphoethanolamine phosphodiesterase activity. Involved in several processes, including activation of phospholipase C activity; negative regulation of potassium ion transport; and positive regulation of smooth muscle cell proliferation. Located in caveola; cytosol; and synapse. Part of heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome; congestive heart failure; and familial multiple nevi flammei. Orthologous to human GNAQ (G protein subunit alpha q). [provided by Alliance of Genome Resources, Apr 2022]