Dbn1 - drebrin 1

Enables actin filament binding activity; cytoskeletal motor inhibitor activity; and profilin binding activity. Involved in several processes, including positive regulation of cell development; regulation of nervous system process; and regulation of organelle organization. Located in several cellular components, including axon; dendrite; and lamellipodium. Is active in glutamatergic synapse; postsynaptic actin cytoskeleton; and postsynaptic membrane. Colocalizes with actin filament. Biomarker of Parkinson's disease; cognitive disorder; sciatic neuropathy; temporal lobe epilepsy; and transient cerebral ischemia. Orthologous to human DBN1 (drebrin 1). [provided by Alliance of Genome Resources, Apr 2022]