Creb1 - cAMP responsive element binding protein 1

Enables several functions, including Hsp70 protein binding activity; arrestin family protein binding activity; and histone acetyltransferase binding activity. Involved in several processes, including cellular response to growth factor stimulus; learning or memory; and regulation of gene expression. Located in several cellular components, including axon; chromatin; and mitochondrial matrix. Part of transcription regulator complex. Used to study transient cerebral ischemia. Biomarker of Huntington's disease; brain ischemia; and sciatic neuropathy. Orthologous to human CREB1 (cAMP responsive element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]