Actn1 - actinin, alpha 1

Enables cytoskeletal regulatory protein binding activity and protein domain specific binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; focal adhesion assembly; and platelet formation. Located in several cellular components, including cytoskeleton; dendritic spine; and nucleus. Colocalizes with cortical actin cytoskeleton and stress fiber. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 15. Orthologous to human ACTN1 (actinin alpha 1). [provided by Alliance of Genome Resources, Apr 2022]