Acta2 - actin alpha 2, smooth muscle

Predicted to enable protein kinase binding activity. Involved in several processes, including positive regulation of ERK1 and ERK2 cascade; positive regulation of cellular component movement; and positive regulation of hepatic stellate cell activation. Located in cytoplasm and stress fiber. Human ortholog(s) of this gene implicated in Moyamoya disease and thoracic aortic aneurysm. Orthologous to human ACTA2 (actin alpha 2, smooth muscle). [provided by Alliance of Genome Resources, Apr 2022]