Sgpp1 - sphingosine-1-phosphate phosphatase 1

Enables sphingosine-1-phosphate phosphatase activity. Involved in regulation of keratinocyte differentiation. Acts upstream of or within apoptotic signaling pathway and sphingolipid metabolic process. Located in endoplasmic reticulum and membrane. Is expressed in several structures, including adrenal gland; alimentary system; heart; liver; and urinary system. Orthologous to human SGPP1 (sphingosine-1-phosphate phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]