Lat - linker for activation of T cells

Predicted to enable protein kinase binding activity and signaling receptor complex adaptor activity. Predicted to be involved in several processes, including integrin-mediated signaling pathway; intracellular signal transduction; and positive regulation of protein kinase activity. Predicted to act upstream of or within gene expression and lymphocyte homeostasis. Predicted to be located in Golgi apparatus; cell-cell junction; and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of COP9 signalosome. Predicted to be active in immunological synapse. Human ortholog(s) of this gene implicated in immunodeficiency 52. Orthologous to human LAT (linker for activation of T cells). [provided by Alliance of Genome Resources, Apr 2022]