Tbl1xr1 - transducin (beta)-like 1X-linked receptor 1

Enables transcription cis-regulatory region binding activity and transcription corepressor activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including blastocyst hatching; fat pad development; and white fat cell differentiation. Predicted to be located in mitotic spindle and nucleus. Predicted to be part of histone deacetylase complex and transcription repressor complex. Is expressed in early conceptus; secondary oocyte; and thymus primordium. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 41. Orthologous to human TBL1XR1 (TBL1X receptor 1). [provided by Alliance of Genome Resources, Apr 2022]