Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within Notch signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in nucleoplasm. Is expressed in bladder; brain; ureter; and urethra of male. Orthologous to human DTX3 (deltex E3 ubiquitin ligase 3). [provided by Alliance of Genome Resources, Apr 2022]