Cxcr6 - chemokine (C-X-C motif) receptor 6

Enables C-X-C chemokine binding activity and C-X-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human CXCR6 (C-X-C motif chemokine receptor 6). [provided by Alliance of Genome Resources, Apr 2022]