Lrba - LPS-responsive beige-like anchor

Predicted to enable protein kinase A binding activity and protein kinase binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in several cellular components, including endoplasmic reticulum; lysosome; and trans-Golgi network. Is expressed in branchial arch; central nervous system; limb; sensory organ; and somite. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human LRBA (LPS responsive beige-like anchor protein). [provided by Alliance of Genome Resources, Apr 2022]