Apobec3 - apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
Alias:
Arp3
Rfv3
Cem15
Apobec
Gm20117
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable several functions, including hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; identical protein binding activity; and zinc ion binding activity. Involved in negative regulation of transposition and negative regulation of viral genome replication. Acts upstream of or within hematopoietic progenitor cell differentiation; regulation of defense response to virus; and regulation of viral life cycle. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Orthologous to several human genes including APOBEC3F (apolipoprotein B mRNA editing enzyme catalytic subunit 3F). [provided by Alliance of Genome Resources, Apr 2022]