Txn2 - thioredoxin 2

Contributes to peptide-methionine (R)-S-oxide reductase activity; peptide-methionine (S)-S-oxide reductase activity; and protein-disulfide reductase activity. Involved in several processes, including response to axon injury; response to glucose; and response to hypoxia. Located in dendrite; mitochondrion; and neuronal cell body. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 29. Orthologous to human TXN2 (thioredoxin 2). [provided by Alliance of Genome Resources, Apr 2022]