Nr4a1 - nuclear receptor subfamily 4, group A, member 1

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; glucocorticoid receptor binding activity; and protein heterodimerization activity. Involved in several processes, including neurotransmitter secretion involved in regulation of skeletal muscle contraction; response to amphetamine; and response to lipopolysaccharide. Located in nucleus. Used to study Parkinson's disease and chronic kidney disease. Biomarker of mesangial proliferative glomerulonephritis. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1). [provided by Alliance of Genome Resources, Apr 2022]