Dlst - dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

Predicted to enable chaperone binding activity; dihydrolipoyllysine-residue succinyltransferase activity; and heat shock protein binding activity. Predicted to be involved in several processes, including 2-oxoglutarate metabolic process; histone succinylation; and tricarboxylic acid cycle. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; metanephros; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and paraganglioma. Orthologous to human DLST (dihydrolipoamide S-succinyltransferase). [provided by Alliance of Genome Resources, Apr 2022]