Predicted to enable Lys48-specific deubiquitinase activity; Lys63-specific deubiquitinase activity; and thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Located in cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; muscle tissue; and spleen. Orthologous to human DESI2 (desumoylating isopeptidase 2). [provided by Alliance of Genome Resources, Apr 2022]