Nol3 - nucleolar protein 3 (apoptosis repressor with CARD domain)

Enables death effector domain binding activity and death receptor binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; negative regulation of cell death; and regulation of signal transduction. Acts upstream of or within regulation of gene expression; response to hypoxia; and response to injury involved in regulation of muscle adaptation. Located in mitochondrion and sarcoplasm. Is expressed in adrenal gland; brain; lung; metanephros; and musculature. Orthologous to human NOL3 (nucleolar protein 3). [provided by Alliance of Genome Resources, Apr 2022]