Brd8 - bromodomain containing 8

Predicted to enable nuclear receptor coactivator activity and thyroid hormone receptor binding activity. Predicted to be involved in cellular response to thyroid hormone stimulus; histone acetylation; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization and regulation of growth. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of NuA4 histone acetyltransferase complex and Swr1 complex. Is expressed in early conceptus; ganglia; genitourinary system; heart; and limb mesenchyme. Orthologous to human BRD8 (bromodomain containing 8). [provided by Alliance of Genome Resources, Apr 2022]